
REJUVENATE
AND REGENERATE YOUR SKIN
Polynucleotides are the latest revolutionary tools in regenerative medicine that work on a cellular level to repair tissue and boost skin quality.
They work by stimulating fibroblasts which encourages cell turnover, improves elasticity, boosts collagen production and hydrates skin thanks to powerful wound-healing polymers.
Polynucleotides also calm inflammation and rebalance melanocyte activity to create an even and refreshed skin tone.
Plinest Polynucleotide-HPT
Experience the future of skincare with Polynucleotide-HPT (Highly Purified Technology), the cutting-edge polynucleotide-based injectable gels that work on a cellular level to transform your skin. These revolutionary treatments harness the power of polymerised polynucleotides, scientifically designed to repair and regenerate tissue, improve elasticity, and stimulate collagen production.
High Purification Technology (HPT) in polynucleotide treatments ensures the highest quality and purity of the product. This advanced process removes impurities, maximising the effectiveness of the polynucleotides to promote skin rejuvenation, boost collagen, and improve elasticity. With HPT, you get a more potent and reliable treatment for smoother, more radiant skin.
Polynucleotide-HPT enhances skin quality by promoting healthy cell turnover, deeply hydrating, and rejuvenating from within. Its wound-healing polymers calm inflammation and help balance melanocyte activity, resulting in an even, radiant skin tone.
Polynucleotide-HPT offers effective solutions for every concern. This versatile treatment is also perfect for revitalizing the scalp (PLINEST HAIR), neck, décolletage, inner arms, thighs, knees, and even the intimate areas.
At Dermaline Aesthetics, we harness the regenerative potential of polynucleotides to provide our patients with safe, effective, and natural-looking results.

AT A GLANCE
TREATMENT TIME
60 Minutes
TREATMENT ANAESTHESIA
Topical Numbing Cream
TREATMENT DOWNTIME
Minor swelling, bruising, redness in treated area
TREATMENT FREQUENCY
3 sessions 3-4 weeks apart
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Why choose Dermaline Aesthetics for anti-wrinkle treatments?As a registered nurse and advanced aesthetics practitioner, Charlotte Cliffe combines medical expertise with an artistic eye for natural-looking results. Our Berkhamsted clinic provides a professional, clinical environment where safety and personalised care are paramount.
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What happens during the consultation?Your consultation with Charlotte includes a thorough facial assessment and discussion of your concerns. The £25 consultation deposit is redeemable against treatment, ensuring dedicated time to create your personalised treatment plan.
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How do anti wrinkle treatments work?Anti-wrinkle treatments are advanced injectable treatments used to reduce the appearance of wrinkles and fine lines on the face. The treatment works by temporarily relaxing specific facial muscles that cause dynamic wrinkles. As an advanced aesthetics practitioner, Charlotte Cliffe precisely targets areas such as the forehead, between the eyebrows (frown lines), and around the eyes (crow's feet) to create natural-looking results that typically last 3-4 months.
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Do anti wrinkle injections hurt?Most clients experience minimal discomfort during treatment. As a registered nurse, Charlotte uses precise injection techniques and can offer topical numbing cream if needed. The treatment is quick, typically taking just 15-30 minutes to complete.
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When will I see results?Results develop gradually over 3-14 days, with optimal results visible after 2 weeks. This ensures a natural-looking enhancement that doesn't appear obvious or overdone.
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How long do anti wrinkle treatments last?The effects of your anti-wrinkle treatment will typically last between three to four months, depending on the individual and the treated area. After this time, the muscles will gradually regain their movement, and the wrinkles and lines will start to reappear. It is recommended to schedule follow-up appointments to maintain the desired results. At Dermaline Aesthetics, Charlotte will customise a treatment plan for you and provide you with expert advice on how often you should receive anti-wrinkle injections to achieve the best results.
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What aftercare should I follow?Post-treatment care is straightforward. For optimal results, we recommend: • Avoiding strenuous exercise for 24 hours • Staying upright for 4 hours after treatment • Not touching or massaging the treated areas • Avoiding alcohol and blood-thinning medications We provide comprehensive aftercare instructions and stock iS CLINICAL skincare products to support your skin health post-treatment.
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Can I combine anti-wrinkle treatments with other treatments?Yes, anti-wrinkle treatments can be effectively combined with other treatments like dermal fillers, HIFU, or RF microneedling for comprehensive rejuvenation. During your consultation, we can discuss the best treatment combination for your goals.
Polynucleotides
Course of 3 treatments: £750
Maintenance treatment: £300

Polynucleotide treatments are versatile and can be used to address various areas of concern. Common treatment areas include the face, neck, décolletage, hands, and other body areas where skin rejuvenation is desired. They are especially effective when used around the delicate eye area. Whether targeting specific wrinkles or overall skin quality, polynucleotide therapy offers a comprehensive approach to aesthetic enhancement.